![]() This in turn aid stem cells in restoring localized or systemic conditions for normal healing and tissue regeneration. Studies have shown that their related anti-inflammatory, trophic, paracrine and immuno-modulatory functions tend to elicit even greater therapeutic effects in association with these cells. Mesenchymal stem cells (MSCs) are defined as adult native cells that have the ability to differentiate into tissues including, but not limited to, bone, cartilage and adipose cells in vitro (Fig. Stem cells (embryonic stem cells and adult stem cells) serve as the primary instrument of tissue engineering, a technology that has garnered a great deal of attention in civil and military research for providing possible treatment of many diseases and injuries (Fig. Through these techniques, organ failure can be addressed by the implantation of engineered, semi-synthetic tissues or whole organs that mimic the native function. It is a science that combines stem cells, scaffolds with suitable growth factors, cytokines and chemokines to improve, replace or regenerate tissues and organs (Fig. Tissue engineering is an emerging field representing potential alternatives to contemporary solutions. Unfortunately, most of these procedures can neither restore nor sustain a wounded tissue or organ over the long term there is therefore an urgent need for lasting and complementary methods. The treatment options currently available include medication, surgical repair, transplants of allograft or xenograft tissue, artificial prostheses and mechanical devices. Wounds resulting from injuries suffered during active military service represent major challenges to defense health systems, accounting for huge military expenditures in the US, Russia, Ukraine, Iraq, Syria, Afghanistan, Yemen, Sudan and other areas around the world with active conflicts. Injuries that would have resulted in deaths previously now result in wounds today similarly, today’s permanent wounds may be reduced to tomorrow’s bad memories with further advances in stem cell-based therapies. Current military applications of stem cell-based therapies are already saving the lives of soldiers who would have died in previous conflicts. The new research developments in these areas suggest that solutions are being developed to reduce critical consequences of wounds and exposures suffered in warfare. These applications include the treatment of injuries to the skin, sensory organs, nervous system tissues, the musculoskeletal system, circulatory/pulmonary tissues and genitals/testicles and of acute radiation syndrome and the development of novel biosensors. Therefore, the use of stem cells holds significant promise for the treatment of many battlefield injuries and their complications. Recent reports have suggested the greater therapeutic effects of the anti-inflammatory, trophic, paracrine and immune-modulatory functions associated with these cells, which induce them to restore normal healing and tissue regeneration by modulating immune reactions, regulating inflammation, and suppressing fibrosis. ![]() ![]() Human development depends intimately on stem cells, the mysterious precursor to every kind of cell in the body that, with proper instruction, can grow and differentiate into any new tissue or organ. In this review, discussions focus on the applications of stem cells in tissue engineering to address health risks frequently faced by combatants at war. Tissue engineering has emerged as a field with the potential to provide contemporary solutions. The dynamic nature of modern warfare, including threats and injuries faced by soldiers, necessitates the development of countermeasures that address a wide variety of injuries.
0 Comments
Leave a Reply. |